AI overview
AI generated. Not medical advice.What it's for
Everyday immune support, antioxidant support, seasonal wellness
Who it may fit
Adults with busy lifestyles seeking on-hand seasonal defence support or those with low fruit and mushroom intake looking for convenient phytonutrient support.
Key actives per serving
- Grapefruit Seed Extract: 250 mg
- Vitamin C (as calcium ascorbate): 125 mg (207% DV)
- Zinc (as gluconate): 5 mg (33% DV)
- Reishi Mushroom Extract (4:1): 100 mg
- Echinacea angustifolia Extract (4:1): 50 mg
How to take
Take 1 tablet once daily with or without food for up to two weeks at first signs of imbalance; taking with food may support comfort if you are sensitive to acids.
Diet / Allergen fit
Gluten Free; Made without soya, milk, egg, yeast, wheat, sweeteners, preservatives, and GMOs; Not tested on animals; Contains no stated major allergens.
Ingredients explained
Grapefruit Seed Extract
Provides polyphenols such as naringenin that may interact with microbial membranes and oxidative processes, supporting natural defence functions.
Caution: Grapefruit compounds may affect how some medicines are broken down in the body; consult a professional if taking medications.
Vitamin C (as calcium ascorbate)
Functions as an antioxidant and cofactor for enzymes involved in collagen and catecholamine synthesis, supporting cellular defence and barrier integrity.
Caution: May cause mild stomach upset in some people; taking with food can enhance comfort.
Zinc (as gluconate)
Serves as a cofactor for numerous enzymes and supports normal development and function of immune cells.
Caution: High zinc intake can interfere with copper balance; avoid combining with high-dose zinc from other supplements.
Reishi Mushroom Extract (4:1)
Contains beta-glucans and triterpenes that may modulate innate and adaptive immune cell signalling.
Caution: Mushroom extracts may not suit those with mushroom sensitivities; discontinue if unusual reactions occur.
Echinacea angustifolia Extract (4:1)
Provides phenolic compounds that may influence macrophage activity and cytokine signalling.
Caution: People with ragweed or daisy family sensitivities may react; monitor for allergy-like symptoms.
How they work together
Vitamin C and zinc provide foundational antioxidant and enzymatic support, while grapefruit seed extract and ginger add polyphenols that interact with microbial and oxidative pathways. Reishi and other mushroom extracts supply beta-glucans that influence immune cell signalling, and botanicals like echinacea, astragalus, yarrow, and Oregon grape root add diverse phytochemicals that act on complementary defence mechanisms.
Safety and tips
Label Warning: Do not exceed the suggested use. Not recommended for use during pregnancy unless advised by a licensed healthcare professional. Not for children under 12 years old.
Who should be cautious: People with citrus or grapefruit sensitivities. Those on medications affected by grapefruit extract, such as certain statins and calcium channel blockers, should discuss with a healthcare provider before use. Individuals with ragweed or daisy family sensitivities may react to echinacea or yarrow. Those with hormone-sensitive conditions should be cautious with echinacea. People with liver concerns should use caution due to Oregon grape root. If you take medications that may interact with grapefruit extract, consult a healthcare provider before combining.
Product rankings:
iHerb Quality Promise
This product is guaranteed authentic and backed by our easy returns and refunds policy. Details
Grapefruit Seed Extract may support gut health, and probiotics can enhance beneficial gut bacteria, promoting a balanced digestive system.
AI generated. Not medical advice.
Overview
- Where Science Works Naturally®
- 250 mg Grapefruit Seed Extract
- With Echinacea, Astragalus, Vitamin C, Mushroom Extracts, Oregon Grape Root & Ginger Root
- Dietary Supplement
- Naturally Fresh - Nitro Pak® - Bacteria Free Environment
- Not Tested On Animals
- Gluten Free
NutriBiotic DefencePlus® Tablets are a unique formulation combining grapefruit seed extract, vitamin C, echinacea extract, astragalus root, ginger root extract, Oregon grape root, yarrow extract, zinc, and the mushroom extracts of reishi, maitake, and shiitake and are used by healthcare professionals worldwide.
Specifications
- First available: 05/2007
-
Delivery weight:
0.18 kg
- Product Code: NBC-01015
- UPC: 728177010157
- Package quantity: 90 Count
- Dimensions: 10.9 x 6.1 x 6.1 cm , 0.18 kg
Suggested use
At first signs of imbalance or lowered resistance, take one tablet daily with or without meals for two weeks. Not recommended for children under 12 years old.
Other ingredients
Microcrystalline cellulose (binder), dicalcium phosphate, stearic acid, dextrose, silica dioxide, magnesium stearate (vegetable lubricant), and natural food glaze coating.
Made without soya, milk, egg, yeast, wheat, sweeteners, preservatives, and GMOs.
Warnings
Keep out of reach of children. Do not exceed suggested use or use during pregnancy without consulting a licensed healthcare professional.
Disclaimer
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally be despatched with alternative packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and do not rely solely on the information provided by iHerb. This website has been machine translated as a courtesy to customers. iHerb does not represent or warrant that the translations are complete or error-free and iHerb is not responsible for any translation errors or omissions.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Servings Per Container: 90 | ||
| Amount Per Serving | % DV | |
| Vitamin C (as Meta-C® calcium ascorbate) | 125 mg | 207% |
| Zinc (gluconate) | 5 mg | 33% |
| Grapefruit Seed Extract | 250 mg | * |
| Astragalus Root | 100 mg | * |
| Reishi Mushroom Extract (4:1) | 100 mg | * |
| Echinacea Angustifolia Extract (4:1) | 50 mg | * |
| Ginger Root Extract (6:1) | 50 mg | * |
| Maitake Mushroom Extract (4:1) | 50 mg | * |
| Oregon Grape Root | 50 mg | * |
| Shiitake Mushroom Extract (4:1) | 50 mg | * |
| Yarrow Extract (6:1) | 50 mg | * |
| * Daily value (DV) not established. | ||